In the third episode of our limited series Knowledge Symbiosis: Can Biomimicry and Indigenous Science Harmonize?, PennElys Droz and Maibritt Pederson Zari engage in conversation hosted by Lily Urmann, exploring cosmologies, paradigm shifts and how to be in good relationship while we co-create and design as humans within creation. They outline principles of regenerative design in communities, and how we all might engage in decolonization as well as learn from Indigenous ecological relationships. This limited series is produced by The Cultural Conservancy'sNative Seed Pod, Arizona State University, and Learning From Nature: The Biomimicry Podcast, with music and soundscapes by Colin Farish.